Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580034 | 0.87 | KCNK9 (0.72) | KCNK9PKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6579950 | 0.85 | NPC1 (0.73) | NR1H4LMNANPC1MAPTRAB9A | |
| SCHEMBL6580158 | 0.84 | KMT2A (0.54) | NR1H4KCNK9HTTLMNAPKM | |
| SCHEMBL6577705 | 0.82 | NR1H4 (0.78) | NR1H4LMNANPC1MAPTRAB9A | |
| SCHEMBL6580077 | 0.82 | NR1H4 (0.70) | NR1H4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6580248 | 0.82 | NR1H4 (0.57) | NR1H4KCNK9POLBNPC1MAPT | |
| SCHEMBL7477030 | 0.82 | NR1H4 (0.52) | NR1H4KCNK9HTTTDP1NPC1 | |
| SCHEMBL6346822 | 0.82 | KCNK3 (0.71) | KCNK9HTTPOLBNPC1MAPT | |
| SCHEMBL6582800 | 0.81 | KCNK9 (0.64) | KCNK9PKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27916078 | 0.80 | KMT2A (0.55) | HTTLMNATDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |