Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17360649 | 0.78 | KMT2A (0.41) | L3MBTL1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL23886963 | 0.77 | CYP3A4 (0.59) | CYP3A4CYP2C19L3MBTL1KMT2ACHRM2 | |
| SCHEMBL19347151 | 0.77 | KMT2A (0.46) | CYP3A4CYP2C19KMT2ACHRM2CHRM4 | |
| SCHEMBL5718440 | 0.76 | CHRM2 (0.46) | CYP3A4CYP2C19L3MBTL1KMT2ACHRM2 | |
| SCHEMBL7209211 | 0.76 | L3MBTL1 (0.46) | CYP3A4CYP2C19L3MBTL1KMT2ACHRM2 | |
| SCHEMBL2312332 | 0.76 | MEN1 (0.53) | CYP3A4CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL23904643 | 0.74 | CYP3A4 (0.60) | CYP3A4CYP2C19L3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2309353 | 0.74 | MEN1 (0.51) | CYP3A4CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL5563143 | 0.72 | KMT2A (0.48) | CYP3A4CYP2C19KMT2ACHRM2CHRM4 | |
| SCHEMBL5848569 | 0.72 | SLC6A2 (0.52) | KMT2ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9263577-A | — | — | None | — | — | JP | disclosed |
| EP-1221443-B1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |
| JP-H09263577-A | DIPHENYLMETHYL-AZETIDINONE COMPOUND AND ELASTASE INHIBITOR | JAPAN TOBACCO INC | 1997-10-07 | — | — | JP | disclosed |
| WO-1996029307-A1 | DIPHENYLMETHYL-AZETIDINONE COMPOUNDS AND ELASTASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 1996-09-26 | — | — | WO | disclosed |
| US-4190579-A | Synthesis of beta-lactams from azetidine carboxylic acid esters | RESEARCH CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |