Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581880 | 0.86 | POLB (0.43) | POLBNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6582004 | 0.84 | POLB (0.40) | POLBNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6580167 | 0.81 | ERCC5 (0.45) | POLBTSHRLMNAALDH1A1HTT | |
| SCHEMBL6577327 | 0.74 | HPGD (0.54) | TSHRLMNAALDH1A1RAB9AHPGD | |
| SCHEMBL11271744 | 0.73 | HPGD (0.53) | TSHRLMNAALDH1A1RAB9AHPGD | |
| SCHEMBL6299886 | 0.73 | SLC9A1 (0.63) | POLBNPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25333396 | 0.72 | EGLN1 (0.54) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17727586 | 0.72 | NPC1 (0.69) | NPC1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6579893 | 0.71 | HPGD (0.41) | TSHRNPSR1LMNAALDH1A1HTT | |
| SCHEMBL5815409 | 0.71 | POLB (0.56) | POLBNPC1SLC9A1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-B1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL CO (JP) | 2004-02-18 | — | — | EP | disclosed |
| US-5597929-A | Production process of 2-(tetrazol-5-yl)-4-oxo-4H-benzopyran | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |