Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.62 |
| ▸ | CTSL | P07711 | 8/20 | 0.62 |
| ▸ | CTSS | P25774 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578054 | 0.85 | CTSK (0.64) | CTSKCTSLCTSSCTSBCASP1 | |
| SCHEMBL6580085 | 0.80 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580090 | 0.80 | CTSK (0.69) | CTSKCTSLCTSSCTSB | |
| SCHEMBL27474580 | 0.77 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7341826 | 0.77 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6578212 | 0.77 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6577860 | 0.77 | CTSK (1.00) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6580413 | 0.76 | CTSK (0.89) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7664197 | 0.75 | CTSK (0.73) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4686510 | 0.74 | CTSK (1.00) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936912-B1 | INHIBITORS OF CYSTEINE PROTEASE | SMITHKLINE BEECHAM CORP (US) | 2004-02-11 | — | — | EP | claimed |