Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582737 | 0.79 | ALDH1A1 (0.36) | POLBALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL6583060 | 0.78 | KMT2A (0.41) | POLBALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL6583645 | 0.78 | ALDH1A1 (0.35) | POLBALDH1A1KMT2ANAAACYP4F2 | |
| SCHEMBL6580461 | 0.77 | CYP4F2 (0.42) | POLBALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL6582020 | 0.76 | NPC1 (0.35) | POLBALDH1A1KMT2ANAAACYP4F2 | |
| SCHEMBL17860704 | 0.74 | ALDH1A1 (0.48) | POLBALDH1A1NAAALMNA | |
| SCHEMBL2289682 | 0.74 | SMN1; SMN2 (0.44) | POLBALDH1A1KMT2ALMNA | |
| SCHEMBL31050190 | 0.73 | CYP3A4 (0.39) | POLBALDH1A1KMT2ACYP4F2CYP4A11 | |
| SCHEMBL16701074 | 0.72 | CYP4F2 (0.37) | POLBKMT2ACYP4F2CYP4A11 | |
| SCHEMBL7548982 | 0.71 | CHRM2 (0.38) | POLBALDH1A1KMT2ACYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154993-B1 | THIOAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | disclosed |