Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582737 | 0.86 | ALDH1A1 (0.36) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL6583645 | 0.84 | ALDH1A1 (0.35) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL31050190 | 0.83 | CYP3A4 (0.39) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL11303514 | 0.81 | CYP4F2 (0.41) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL17454 | 0.80 | SMN1; SMN2 (0.40) | LMNAKCNH2HSD17B10MEN1KMT2A | |
| SCHEMBL1142569 | 0.79 | SMN1; SMN2 (0.39) | LMNAHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL1814127 | 0.77 | CYP4F2 (0.40) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL17882031 | 0.76 | HCAR2 (0.36) | CHRM2CHRM1CYP3A4SIGMAR1LMNA | |
| SCHEMBL2289682 | 0.76 | SMN1; SMN2 (0.44) | LMNAKCNH2HSD17B10MEN1KMT2A | |
| SCHEMBL15142237 | 0.75 | ALOX5 (0.34) | CHRM2CHRM1CYP3A4SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010338-A1 | PHENYL-KETO-IMIDAZOLIDINE THIOAMIDE DERIVATIVES | HULL KENNETH G (US) | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010338-A1 | PHENYL-KETO-IMIDAZOLIDINE THIOAMIDE DERIVATIVES | VCAM1, ICAM1, KCNA4 | CHRM2 1814/4885CHRM1 1277/4885CYP3A4 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.