Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.67 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.57 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.57 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.57 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609466 | 0.93 | NPC1 (0.59) | PDPK1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL3732559 | 0.86 | CES2 (0.56) | PDPK1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL7194757 | 0.85 | TACR1 (0.51) | PDPK1NPC1RAB9ATDP1CASP3 | |
| SCHEMBL6201845 | 0.85 | MMP1 (0.54) | PDPK1NPC1RAB9AFFAR1MMP1 | |
| SCHEMBL10769738 | 0.84 | TDP1 (0.70) | PDPK1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5608126 | 0.83 | ESRRG (0.63) | PDPK1NPC1RAB9ATDP1CASP3 | |
| SCHEMBL1040696 | 0.83 | PIK3CA (0.55) | PDPK1NPC1RAB9AHSD11B1PTPN1 | |
| Hydrochloric Acid SCHEMBL5752228 | 0.83 | MMP1 (0.51) | PDPK1NPC1RAB9AFFAR1MMP1 | |
| SCHEMBL27952195 | 0.83 | CES2 (0.56) | PDPK1NPC1RAB9ATDP1CASP3 | |
| SCHEMBL28423545 | 0.83 | FFAR4 (0.53) | NPC1RAB9ATDP1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059949-A | Two-dimensional perovskite and preparation method and application thereof | 中山大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-116102430-A | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-111807971-B | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-111807971-A | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-106478325-B | A method of synthesis alpha-alkyl ketone | 南京理工大学 | 2019-06-25 | — | — | CN | disclosed |
| CN-105439787-B | Method for synthesizing α -alkyl ketone | 南京理工大学 | 2018-02-13 | — | — | CN | disclosed |
| CN-106478325-A | A kind of method of synthesis alpha-alkyl ketone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-105906543-A | Novel synthesis method of multifunctional pyrrole | 常州大学 | 2016-08-31 | — | — | CN | disclosed |
| CN-105439787-A | Method for synthesizing alpha-alkyl ketone | UNIV NANJING SCIENCE & TECH | 2016-03-30 | — | — | CN | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | PDPK1 109/4885PLAAT3 1629/4885PLAAT5 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.