Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30789227 | 1.00 | MAOB (0.56) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL658101 | 0.90 | MAOB (0.61) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL30141054 | 0.90 | MAOB (0.61) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10147478 | 0.88 | MAPT (0.53) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL756911 | 0.85 | MAOB (0.57) | MAOBMAPTSLC5A1SLC5A2HPGD | |
| SCHEMBL18526952 | 0.84 | MAOB (0.51) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL30892463 | 0.83 | MAOB (0.76) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL1728168 | 0.83 | MAOB (0.76) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL14181066 | 0.83 | MAOB (0.68) | MAOBCYP2C19SMN1; SMN2L3MBTL1SLC5A1 | |
| SCHEMBL11739144 | 0.81 | MAOB (0.59) | MAOBMAPTCYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181293-B2 | Method for the synthesis of aspalathin and analogues thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2015-11-10 | — | — | US | disclosed |
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | SOUTH AFRICAN MEDICAL RESEARCH COUNCIL (ZA) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018182-A1 | Method for the Synthesis of Aspalathin and Analogues Thereof | ASPH, C9, ALDH3A1 | MAOB 1865/4885MAPT 3291/4885CYP2C9 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.