Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6581520 | 1.00 | LMNA (0.52) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL8018305 | 1.00 | LMNA (0.52) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL7119395 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL14430058 | 0.84 | KDM4E (0.50) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL6705432 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL5195970 | 0.84 | KDM4E (0.50) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL6705433 | 0.84 | LMNA (0.55) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL5195973 | 0.84 | KDM4E (0.50) | LMNATSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL3688001 | 0.82 | RAB9A (0.47) | HPGDKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9022614 | 0.82 | MAPT (0.40) | LMNATSHRHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194416-B1 | HALOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2004-09-08 | — | — | EP | claimed |
| US-6683029-B1 | Halopyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 2004-01-27 | — | — | US | disclosed |
| CN-1058011-C | 13-substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-11-01 | — | — | CN | disclosed |
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| CN-1112119-A | 13-substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 1995-11-22 | — | — | CN | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |