SCHEMBL7192060

SCHEMBL7192060

CC(N=C=O)c1cccc(C(C)N=C=O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 3/20 0.45
CYP3A4 P08684 3/20 0.34
HDAC4 P56524 3/20 0.34
HDAC8 Q9BY41 3/20 0.34
KDM4E B2RXH2 3/20 0.34
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HDAC2 Q92769 2/20 0.34
MDM4 O15151 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
TP53 P04637 1/20 0.34
TYR P14679 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CA5A P35218 1/20 0.34
HTT P42858 1/20 0.34
MDM2 Q00987 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL7062390 0.98 MIF (0.44) MIFCYP3A4HDAC4HDAC8KDM4E
SCHEMBL27978547 0.88 ACP3 (0.41) MIFCYP3A4ALDH1A1HPGDMAPK1
SCHEMBL27978548 0.88 ACP3 (0.41) MIFCYP3A4ALDH1A1HPGDMAPK1
SCHEMBL14405638 0.88 ACP3 (0.41) MIFCYP3A4ALDH1A1HPGDMAPK1
SCHEMBL15620939 0.87 PNMT (0.41) MIFALDH1A1HPGDMEN1KMT2A
SCHEMBL30483583 0.87 PNMT (0.41) MIFALDH1A1HPGDMEN1KMT2A
SCHEMBL15620938 0.87 PNMT (0.41) MIFALDH1A1HPGDMEN1KMT2A
SCHEMBL27721627 0.87 HSD11B1 (0.41) MIFHDAC4MEN1KMT2A
SCHEMBL15034708 0.87 MIF (0.51) MIFCYP3A4HDAC4HDAC8KDM4E
SCHEMBL476029 0.85 CYP3A4 (0.40) MIFCYP3A4TDP1GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115011053-B High-reflection fractal structure hydrogel, and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2023-08-01 CN claimed
US-5733959-A CONTAINING CARBODIIMIDE BASF AKTIENGESELLSCHAFT (DE) 1998-03-31 US claimed
EP-0794974-A1 STABILIZED POLYESTER SHAPING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1997-09-17 EP claimed
WO-1996017011-A1 STABILIZED POLYESTER SHAPING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1996-06-06 WO claimed
EP-0530141-A1 Radiation curable composition with high temperature oil resistance CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-5183831-A Acylated polyurethanes CIBA-GEIGY CORPORATION (US) 1993-02-02 US claimed
US-4420600-A CURING WITH DIOL, AMINODIOL, AND CATALYST AMERICAN CYANAMID COMPANY (US) 1983-12-13 US claimed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12503427-B2 Diamine composition, and method of preparing diisocyanate composition SK pucore co., ltd (KR) 2025-12-23 US disclosed
EP-3689932-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER RESIN, OPTICAL MEMBER RESIN, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD (TH) 2025-07-30 EP disclosed
US-20250188024-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-12 US disclosed
US-20250179014-A1 METHOD OF PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLATE, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2025-06-05 US disclosed
US-5183831-A Acylated polyurethanes CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed
EP-0316446-A4 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD 1991-03-20 EP disclosed
EP-0178525-B1 PROCESS FOR THE PREPARATION OF HIGH MOLECULAR WEIGHT AMINO COMPOUNDS WITH LOWERED AMINE MONOMER CONTENT AS WELL AS THEIR USE BAYER AG (DE) 1990-10-03 EP disclosed
EP-0316446-A1 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD CREST-FOAM Corp. (US) 1989-05-24 EP disclosed
WO-1988009350-A1 IMPROVED CONDUCTIVE POLYURETHANE FOAM COMPOSITIONS AND METHOD CREST-FOAM COPORATION (US) 1988-12-01 WO disclosed
EP-0104683-B1 PROCESS FOR COATING AN ELECTRICALLY CONDUCTIVE SUBSTRATE AND AN AQUEOUS COMPOSITION CONTAINING A CATIONIC BINDER AKZO N.V. (NL) 1986-09-10 EP disclosed
US-4420600-A CURING WITH DIOL, AMINODIOL, AND CATALYST AMERICAN CYANAMID COMPANY (US) 1983-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503427-B2 Diamine composition, and method of preparing diisocyanate composition INCENP, ALKBH5, TET1 MIF 3016/4885CYP3A4 3512/4885HDAC4 3750/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 MIF 1569/4885CYP3A4 4631/4885HDAC4 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.