Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480770 | 0.91 | ALDH1A1 (0.84) | ALDH1A1MAPTTP53ADRA1BHTR1A | |
| SCHEMBL2317791 | 0.90 | ALDH1A1 (0.82) | ALDH1A1MAPTTP53ADRA1BHTR1A | |
| SCHEMBL6582011 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ADRA1BHTR1ANPSR1ADRA1D | |
| SCHEMBL6577757 | 0.84 | ALDH1A1 (0.73) | ALDH1A1ADRA1BHTR1AADRA1DADRA1A | |
| SCHEMBL4739641 | 0.83 | ALDH1A1 (0.70) | ALDH1A1ADRA1BHTR1A | |
| SCHEMBL22350694 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPTTP53ADRA1BHTR1A | |
| Ammonia Solution, Strong SCHEMBL2318516 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MAPTTP53ADRA1BHTR1A | |
| SCHEMBL7410473 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTADRA1BHTR1AADRA1D | |
| SCHEMBL19403575 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTTP53ADRA1BHTR1A | |
| SCHEMBL2316128 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTTP53ADRA1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |
| EP-1200406-B1 | CYCLIC AMIDES AND IMIDES HAVING SELECTIVE ANTAGONIST ACTIVITY AT ALPHA-1D ADRENERGIC RECEPTOR | RECORDATI CHEM PHARM (IT) | 2004-11-24 | — | — | EP | disclosed |