Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588792 | 0.96 | DDB1 (0.37) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL6587180 | 0.95 | DDB1 (0.39) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL6588345 | 0.94 | ADRB3 (0.36) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL9385137 | 0.86 | ADRB3 (0.40) | ADRB3MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL9654014 | 0.86 | PDE7A (0.38) | — | |
| SCHEMBL9385378 | 0.85 | ALDH1A1 (0.39) | ADRB3ALDH1A1 | |
| SCHEMBL23264604 | 0.84 | ADRB3 (0.38) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL9385975 | 0.84 | HTR1B (0.41) | ADRB3 | |
| SCHEMBL10577194 | 0.83 | ADRB3 (0.34) | ADRB3 | |
| SCHEMBL9384640 | 0.82 | ADRB3 (0.40) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |