Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588792 | 0.99 | DDB1 (0.37) | DDB1CRBNADRB3MEN1ALDH1A1 | |
| SCHEMBL6583309 | 0.95 | ADRB3 (0.36) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL6588345 | 0.92 | ADRB3 (0.36) | ADRB3MEN1ALDH1A1GAATSHR | |
| SCHEMBL9385378 | 0.83 | ALDH1A1 (0.39) | ADRB3ALDH1A1 | |
| SCHEMBL23264604 | 0.82 | ADRB3 (0.38) | DDB1CRBNADRB3MEN1ALDH1A1 | |
| SCHEMBL9385975 | 0.82 | HTR1B (0.41) | ADRB3 | |
| SCHEMBL9385137 | 0.81 | ADRB3 (0.40) | ADRB3MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL9654014 | 0.81 | PDE7A (0.38) | — | |
| SCHEMBL9384640 | 0.80 | ADRB3 (0.40) | ADRB3 | |
| SCHEMBL9384972 | 0.78 | ADRB3 (0.40) | DDB1CRBNADRB3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |