Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583396 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ALOX15SMN1; SMN2CXCR3TDP1 | |
| SCHEMBL2588454 | 0.98 | ALDH1A1 (0.53) | ALDH1A1ALOX15SMN1; SMN2CXCR3TDP1 | |
| SCHEMBL6588086 | 0.92 | ALDH1A1 (0.46) | ALDH1A1ALOX15SMN1; SMN2TDP1KMT2A | |
| SCHEMBL1054489 | 0.76 | CXCR3 (0.42) | ALDH1A1ALOX15SMN1; SMN2CXCR3PKM | |
| SCHEMBL1051261 | 0.76 | CXCR3 (0.42) | ALDH1A1ALOX15SMN1; SMN2CXCR3PKM | |
| SCHEMBL1054487 | 0.76 | CXCR3 (0.42) | ALDH1A1ALOX15SMN1; SMN2CXCR3PKM | |
| SCHEMBL10881311 | 0.76 | CXCR3 (0.41) | ALDH1A1ALOX15SMN1; SMN2CXCR3NPSR1 | |
| SCHEMBL10881315 | 0.76 | CXCR3 (0.41) | ALDH1A1ALOX15SMN1; SMN2CXCR3NPSR1 | |
| SCHEMBL10881322 | 0.76 | CXCR3 (0.41) | ALDH1A1ALOX15SMN1; SMN2CXCR3NPSR1 | |
| SCHEMBL1050390 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |