Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | IDH2 | P48735 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444332 | 0.85 | IDH2 (0.54) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL11114461 | 0.82 | MAPT (0.51) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL6582317 | 0.82 | MAPT (0.45) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL16241281 | 0.81 | KIF11 (0.51) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL30490047 | 0.81 | LMNA (0.53) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL42000 | 0.81 | LMNA (0.53) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL28009480 | 0.79 | P2RX1 (0.44) | MAPTALDH1A1RAPGEF4IDO1LMNA | |
| SCHEMBL6232265 | 0.79 | LMNA (0.63) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL8102983 | 0.79 | MAPT (0.53) | MAPTGAAALDH1A1NPSR1TDP1 | |
| SCHEMBL20714773 | 0.79 | MAPT (0.49) | MAPTGAAALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183101-A1 | PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-17 | — | — | WO | disclosed |
| CN-104642338-A | Methods of pest control in soybean | SYNGENTA PARTICIPATIONS AG | 2015-05-27 | — | — | CN | disclosed |
| EP-0816359-B1 | 4-Amino-2-ureido-pyrimidine-5-carboxamides, processes for their preparation, medicaments containing these compounds, and their use | AVENTIS PHARMA GMBH (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-5773447-A | 4-AMINO-2-UREIDOPYRIMIDINE-5-CARBOXAMIDE FORMED BY AMIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0816359-A1 | 4-Amino-2-ureido-pyrimidine-5-carboxamides, processes for their preparation, medicaments containing these compounds, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-07 | — | — | EP | disclosed |