Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583689 | 0.90 | SIRT2 (0.45) | SIRT2ALDH1A1HSD17B10MAPTKDM4C | |
| SCHEMBL6584720 | 0.89 | MTNR1A (0.52) | SIRT2ALDH1A1HSD17B10MAPTKDM4C | |
| SCHEMBL8889642 | 0.83 | APP (0.44) | SIRT2ALDH1A1HSD17B10MAPTKDM4C | |
| SCHEMBL8889749 | 0.80 | FFAR1 (0.48) | KDM4CKMT2AMEN1BCHE | |
| SCHEMBL6581895 | 0.79 | TAAR1 (0.50) | ALDH1A1CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL6584139 | 0.79 | CYP3A4 (0.49) | MAPTCYP1A2CYP3A4KMT2AMEN1 | |
| SCHEMBL6584243 | 0.79 | PPARG (0.52) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL6583544 | 0.78 | SIRT2 (0.59) | SIRT2ALDH1A1HSD17B10MAPTKDM4C | |
| SCHEMBL6587658 | 0.77 | PPARG (0.52) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL8859197 | 0.77 | FASN (0.45) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |