Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12799076 | 0.88 | ALOX5 (0.54) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL29610155 | 0.88 | ALOX5 (0.54) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL2840795 | 0.87 | FFAR4 (0.55) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL13693266 | 0.87 | RXRA (0.60) | ALOX5OR51E2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL12799848 | 0.86 | IAPP (0.67) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| Glycine SCHEMBL28611645 | 0.86 | ALOX5 (0.47) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL12799919 | 0.85 | IAPP (0.68) | ALOX5OR51E2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1550337 | 0.85 | CYP4F2 (0.56) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL13482377 | 0.84 | ALOX5 (0.50) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL22224207 | 0.84 | ALOX5 (0.49) | ALOX5OR51E2ALDH1A1TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |