Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 12/20 | 0.66 |
| ▸ | MMP3 | P08254 | 12/20 | 0.66 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586818 | 0.90 | MMP3 (0.80) | MMP2MMP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6590166 | 0.88 | MMP2 (0.84) | MMP2MMP3L3MBTL1EGLN1 | |
| SCHEMBL6586576 | 0.87 | MMP2 (0.80) | MMP2MMP3L3MBTL1 | |
| SCHEMBL6586433 | 0.86 | MMP2 (0.85) | MMP2MMP3PPARGPPARAL3MBTL1 | |
| SCHEMBL6590460 | 0.86 | MMP2 (0.72) | MMP2MMP3L3MBTL1EGLN1 | |
| SCHEMBL6587634 | 0.86 | MMP2 (0.82) | MMP2MMP3L3MBTL1EGLN1 | |
| SCHEMBL6586635 | 0.85 | MMP2 (0.85) | MMP2MMP3L3MBTL1EGLN1 | |
| SCHEMBL6587018 | 0.85 | MMP2 (0.66) | MMP2MMP3L3MBTL1 | |
| SCHEMBL6590129 | 0.85 | MMP2 (0.66) | MMP2MMP3L3MBTL1 | |
| SCHEMBL6588532 | 0.84 | MMP2 (0.84) | MMP2MMP3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |