Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583777 | 1.00 | MEN1 (0.62) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL6583771 | 1.00 | MEN1 (0.62) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL6080754 | 0.86 | KMT2A (0.56) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL10874799 | 0.86 | ALDH1A1 (0.66) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL10874791 | 0.86 | ALDH1A1 (0.66) | MEN1KMT2ARAB9AGAACYP2C9 | |
| SCHEMBL6587509 | 0.84 | ABCC1 (0.59) | MEN1KMT2ARAB9ACYP2C9CYP2C19 | |
| SCHEMBL6587318 | 0.80 | ALDH1A1 (0.66) | KMT2ARAB9AGAACYP2C9KCNMA1 | |
| SCHEMBL6589695 | 0.80 | ALDH1A1 (0.52) | KMT2ARAB9ACYP3A4NPSR1KCNMA1 | |
| SCHEMBL6584488 | 0.80 | MAPK1 (0.50) | MEN1KMT2ARAB9AGAANPSR1 | |
| SCHEMBL6589705 | 0.80 | ALDH1A1 (0.52) | KMT2ARAB9ACYP3A4NPSR1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |