Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589698 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1RXFP1CYP3A4 | |
| SCHEMBL6589705 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTNPSR1RXFP1CYP3A4 | |
| SCHEMBL6587315 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPTKCNMA1KDM4EKMT2A | |
| SCHEMBL6587311 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPTKCNMA1KDM4EKMT2A | |
| SCHEMBL6587318 | 0.89 | ALDH1A1 (0.66) | ALDH1A1MAPTKCNMA1KDM4EKMT2A | |
| SCHEMBL6080536 | 0.88 | MAPT (0.51) | ALDH1A1MAPTNPSR1RXFP1CYP3A4 | |
| SCHEMBL6583771 | 0.80 | MEN1 (0.62) | ALDH1A1MAPTNPSR1CYP3A4KCNMA1 | |
| SCHEMBL6583773 | 0.80 | MEN1 (0.62) | ALDH1A1MAPTNPSR1CYP3A4KCNMA1 | |
| SCHEMBL6583777 | 0.80 | MEN1 (0.62) | ALDH1A1MAPTNPSR1CYP3A4KCNMA1 | |
| SCHEMBL10874791 | 0.78 | ALDH1A1 (0.66) | ALDH1A1MAPTNPSR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |