Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320414 | 0.90 | PDE4A (0.46) | MAPTHSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL5914872 | 0.90 | CYP1A2 (0.44) | MAPTHSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL5049785 | 0.86 | SMPD1 (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27998903 | 0.86 | SMPD1 (0.46) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL309719 | 0.83 | KDM4E (0.46) | MAPTHSD17B10KDM4EALDH1A1POLB | |
| SCHEMBL3401420 | 0.82 | FDPS (0.41) | MAPTKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL9117605 | 0.81 | PRKCE (0.46) | MAPTKDM4EALDH1A1POLBMEN1 | |
| SCHEMBL1066757 | 0.80 | THRA (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9116570 | 0.78 | THRA (0.51) | ALDH1A1 | |
| SCHEMBL27720039 | 0.77 | CYP1A2 (0.41) | MAPTKDM4EALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308273-A | 1,6-Naphthyridine derivatives, and antidinic and cerebral circulation improver containing such derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-12-29 | — | — | US | claimed |
| EP-1390354-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | Amgen Inc. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002083653-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-4308273-A | 1,6-Naphthyridine derivatives, and antidinic and cerebral circulation improver containing such derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4105668-A | 6-AMINO-2,2-DIMETHYL-3-(1 -SUBSTITUTED TETRAZOL-5-YL)PENAM COMPOUND REACTED WITH HYDROGEN FLUORIDE | PFIZER INC. (US) | 1978-08-08 | — | — | US | disclosed |