Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 3/20 | 0.52 |
| ▸ | AKT2 | P31751 | 2/20 | 0.52 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214141 | 1.00 | OPRM1 (0.67) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL8660825 | 1.00 | OPRM1 (0.67) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL8660256 | 1.00 | OPRM1 (0.67) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL11199617 | 1.00 | OPRM1 (0.67) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL11223608 | 0.83 | OPRM1 (0.86) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL4914826 | 0.82 | OPRL1 (0.69) | OPRM1OPRK1OPRL1DRD4CYP2D6 | |
| SCHEMBL6586718 | 0.81 | OPRM1 (0.57) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3665096 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OPRL1DRD4AKT1 | |
| SCHEMBL7289653 | 0.78 | ACHE (0.45) | OPRM1OPRK1OPRL1DRD4CYP2D6 | |
| SCHEMBL8863557 | 0.77 | OPRM1 (0.91) | OPRM1OPRK1OPRL1DRD4AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0092391-A2 | Novel piperidine derivatives and pharmaceutical compositions containing same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-10-26 | — | — | EP | disclosed |