Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 17/20 | 0.69 |
| ▸ | EDNRA | P25101 | 3/20 | 0.48 |
| ▸ | EDNRB | P24530 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032708 | 0.90 | DHPS (0.53) | DHPS | |
| SCHEMBL6584032 | 0.90 | DHPS (0.55) | DHPSEDNRAEDNRB | |
| SCHEMBL30466195 | 0.84 | DHPS (0.47) | DHPSEDNRAEDNRB | |
| SCHEMBL5036559 | 0.84 | DHPS (0.65) | DHPS | |
| SCHEMBL4066788 | 0.84 | DHPS (0.85) | DHPSEDNRAEDNRB | |
| SCHEMBL6966755 | 0.83 | EDNRA (0.74) | DHPSEDNRAEDNRB | |
| SCHEMBL30412442 | 0.82 | DHPS (1.00) | DHPSEDNRAEDNRB | |
| SCHEMBL28573181 | 0.82 | DHPS (1.00) | DHPSEDNRAEDNRB | |
| SCHEMBL6961606 | 0.82 | EDNRA (0.66) | DHPSEDNRAEDNRB | |
| SCHEMBL5035326 | 0.82 | DHPS (0.68) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897914-B1 | Process for the preparation of 2,5-disubstitued pyridines | HOFFMANN LA ROCHE (CH) | 2004-05-26 | — | — | EP | claimed |
| EP-0799209-A1 | NOVEL SULFONAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-10-08 | — | — | EP | claimed |
| WO-1996019459-A1 | NOVEL SULFONAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-06-27 | — | — | WO | claimed |