Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1230582 | 0.90 | ALDH1A1 (0.43) | ALDH1A1CYP3A4GLATSHRPOLB | |
| SCHEMBL116805 | 0.90 | ALDH1A1 (0.43) | SIRT2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL8462255 | 0.81 | ALDH1A1 (0.39) | SIRT2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL31143401 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP3A4AHR | |
| SCHEMBL801244 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP3A4AHR | |
| SCHEMBL3345475 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1AHRTSHR | |
| SCHEMBL3491271 | 0.73 | ALDH1A1 (0.37) | KMT2AALDH1A1MAPTGAAHTT | |
| SCHEMBL2404855 | 0.72 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1CYP3A4GLA | |
| SCHEMBL364459 | 0.72 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1AHRMAPT | |
| SCHEMBL29438693 | 0.72 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-B1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2004-08-11 | — | — | EP | disclosed |