⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6584394 | 0.98 | ALDH1A1 (0.31) | — | |
| SCHEMBL9024028 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL7100271 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4428151 | 0.74 | — | — | |
| SCHEMBL6294622 | 0.74 | — | — | |
| SCHEMBL2223785 | 0.74 | — | — | |
| SCHEMBL8223259 | 0.72 | — | — | |
| SCHEMBL195331 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6294621 | 0.72 | — | — | |
| SCHEMBL14584578 | 0.72 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041068-B1 | Compounds for treating and preventing diabetic complications | PFIZER PROD INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-6294538-B1 | ANTIDIABETIC AGENTS AND DIABETIC NEUROPATHY, TREATMENT WITH OXIDOREDUCTASE ENZYMES | PFIZER INC. | 2001-09-25 | — | — | US | disclosed |
| EP-1041068-A1 | Compounds for treating and preventing diabetic complications | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |