Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.49 |
| ▸ | MMP3 | P08254 | 7/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584000 | 0.91 | MMP3 (0.61) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6584658 | 0.91 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6585173 | 0.77 | MMP3 (0.50) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7408826 | 0.74 | MMP2 (0.82) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434601 | 0.73 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587030 | 0.73 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587437 | 0.72 | MMP2 (0.83) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6972569 | 0.72 | MMP2 (0.84) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6588355 | 0.71 | MMP2 (0.70) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6436523 | 0.71 | MMP2 (0.68) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |