Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584975 | 0.84 | PPARA (0.50) | BCHEACHERAB9AL3MBTL1 | |
| SCHEMBL27491559 | 0.84 | PPARA (0.50) | BCHEACHERAB9AL3MBTL1 | |
| SCHEMBL6584598 | 0.84 | PPARA (0.50) | BCHEACHERAB9AL3MBTL1 | |
| SCHEMBL6588340 | 0.78 | BCHE (0.45) | BCHEACHECTSKCACNA1FCACNA1D | |
| SCHEMBL6588263 | 0.78 | HRH1 (0.46) | BCHEACHECACNA1FCACNA1DCACNA1S | |
| SCHEMBL31030159 | 0.77 | CTSK (0.48) | NPC1LMNARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6584496 | 0.76 | PPARA (0.51) | BCHEACHEACERAB9AL3MBTL1 | |
| SCHEMBL6584493 | 0.76 | PPARA (0.51) | BCHEACHEACERAB9AL3MBTL1 | |
| SCHEMBL6585203 | 0.76 | PPARA (0.51) | BCHEACHEACERAB9AL3MBTL1 | |
| SCHEMBL4499378 | 0.74 | BCHE (0.53) | BCHEACHEACEACE2CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815080-B1 | DI-SUBSTITUTED 1,4-PIPERIDINE ESTERS AND AMIDES HAVING 5-HT4 ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM ITALIA (IT) | 2004-06-16 | — | — | EP | disclosed |