Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586135 | 0.99 | MAOA (0.49) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6583217 | 0.97 | DRD2 (0.48) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6585134 | 0.95 | DRD2 (0.46) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6586868 | 0.95 | MEN1 (0.43) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6586857 | 0.94 | MAOA (0.47) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6583577 | 0.93 | MAOA (0.47) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL8312088 | 0.92 | MEN1 (0.41) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6585070 | 0.91 | DRD2 (0.49) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6588676 | 0.89 | DRD2 (0.47) | MAOAMAOBDRD2HRH3DRD3 | |
| SCHEMBL6584864 | 0.88 | MEN1 (0.44) | MAOAMAOBDRD2HRH3DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957100-B1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | KOWA CO (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0957100-A1 | DIAMINE DERIVATIVES AND PHARMACEUTICAL CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 1999-11-17 | — | — | EP | disclosed |