SCHEMBL6585520

SCHEMBL6585520

OC[C@H]1O[C@@H](Oc2ccc(-c3ccccc3)cc2)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 2/20 0.71
▸ SLC5A2 P31639 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23479731 1.00 TYR (0.71) TYRSLC5A2
SCHEMBL14127620 1.00 TYR (0.71) TYRSLC5A2
SCHEMBL12476521 1.00 TYR (0.71) TYRSLC5A2
SCHEMBL6584497 1.00 TYR (0.71) TYRSLC5A2
SCHEMBL14120514 1.00 TYR (0.71) TYRSLC5A2
SCHEMBL20056609 0.94 TYR (0.79) TYR
SCHEMBL1004929 0.91 TYR (0.74) TYR
SCHEMBL21189542 0.91 TYR (0.74) TYR
SCHEMBL21477447 0.91 TYR (0.74) TYR
SCHEMBL9148547 0.91 TYR (0.74) TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773127-B2 Compounds and methods for treating bacterial infections WASHINGTON UNIVERSITY (US) 2023-10-03 — — US disclosed
US-11773127-B2 Compounds and methods for treating bacterial infections WASHINGTON UNIVERSITY (US) 2023-10-03 — — US disclosed
US-20210171563-A1 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS WASHINGTON UNIVERSITY (US) 2021-06-10 — — US disclosed
EP-0778947-B1 CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN LUMIGEN INC (US) 2004-05-12 — — EP disclosed
EP-0516948-B1 Chemiluminescent method and compositions LUMIGEN INC (US) 2000-05-31 — — EP disclosed
US-5686258-A Chemiluminescent detection of hydrolytic enzymes using an acridan LUMIGEN, INC. (US) 1997-11-11 — — US disclosed
EP-0516948-A1 Chemiluminescent method and compositions LUMIGEN, INC. (US) 1992-12-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171563-A1 COMPOUNDS AND METHODS FOR TREATING BACTERIAL INFECTIONS MMP8, ELANE, MPO TYR 273/4885SLC5A2 864/4885
US-11773127-B2 Compounds and methods for treating bacterial infections MMP8, ELANE, MPO TYR 273/4885SLC5A2 864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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