Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6583405 | 0.93 | FFAR1 (0.41) | PPARGFFAR1PPARASMN1; SMN2LMNA | |
| SCHEMBL6587579 | 0.88 | PPARG (0.40) | PPARGMTNR1AMTNR1BLMNAALDH1A1 | |
| SCHEMBL6969226 | 0.86 | FFAR1 (0.41) | PPARGFFAR1PPARAMTNR1AMTNR1B | |
| SCHEMBL6584254 | 0.85 | PPARG (0.41) | PPARGMTNR1AMTNR1BALDH1A1HSD17B10 | |
| SCHEMBL6584217 | 0.85 | KDM4E (0.43) | PPARGPPARAMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL6585536 | 0.84 | PPARG (0.56) | PPARGFFAR1PPARASMN1; SMN2LMNA | |
| SCHEMBL6585583 | 0.83 | PPARG (0.61) | PPARGFFAR1PPARAMTNR1AMTNR1B | |
| SCHEMBL8888965 | 0.83 | PPARG (0.39) | PPARGMTNR1AMTNR1BALDH1A1HSD17B10 | |
| SCHEMBL6969220 | 0.83 | PTPN1 (0.44) | PPARGFFAR1PPARAMTNR1AMTNR1B | |
| SCHEMBL6587026 | 0.82 | PPARG (0.54) | PPARGFFAR1PPARASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |