Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 12/20 | 0.57 |
| ▸ | MMP2 | P08253 | 10/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP14 | P50281 | 2/20 | 0.56 |
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | BCL9 | O00512 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590350 | 0.94 | MMP3 (0.57) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6585861 | 0.87 | MMP3 (0.60) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6586861 | 0.83 | MMP2 (0.52) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6587846 | 0.81 | MMP2 (0.83) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6432618 | 0.81 | MMP2 (0.67) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6440700 | 0.80 | MMP2 (0.71) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6590361 | 0.80 | MMP3 (0.60) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6586333 | 0.80 | MMP2 (0.85) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6436990 | 0.79 | MMP3 (0.69) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6434351 | 0.79 | MMP2 (0.84) | MMP3MMP2MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |