Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585882 | 1.00 | CA12 (0.61) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL5685380 | 0.92 | CA12 (0.55) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL5685375 | 0.92 | CA12 (0.55) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL14253565 | 0.92 | CA12 (0.55) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL13055952 | 0.87 | BACE1 (0.54) | ALOX5KDM4EALDH1A1TNFRSF1AAPP | |
| SCHEMBL5685435 | 0.87 | FDPS (0.74) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL5685199 | 0.87 | KDM4E (0.67) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL5685197 | 0.87 | KDM4E (0.67) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL5685437 | 0.87 | FDPS (0.74) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL7512551 | 0.86 | KDM4E (0.64) | KDM4EALDH1A1HTR1ATNFRSF1AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0783496-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-07-16 | — | — | EP | disclosed |
| WO-1997000249-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-03 | — | — | WO | disclosed |
| CN-1129698-A | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-08-28 | — | — | CN | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| WO-1996005186-A1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-22 | — | — | WO | disclosed |