SCHEMBL5685197

SCHEMBL5685197

CCOC(=O)/C=C/c1ccc(OC)c(OCc2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.67
LMNA P02545 1/20 0.67
FDPS P14324 1/20 0.67
CA12 O43570 1/20 0.66
CA4 P22748 1/20 0.66
CA6 P23280 1/20 0.66
CA5A P35218 1/20 0.66
CA7 P43166 1/20 0.66
CA9 Q16790 1/20 0.66
CA14 Q9ULX7 1/20 0.66
CA5B Q9Y2D0 1/20 0.66
TTR P02766 1/20 0.66
APP P05067 4/20 0.64
MMP1 P03956 4/20 0.64
MMP2 P08253 2/20 0.64
MMP3 P08254 2/20 0.64
MMP9 P14780 2/20 0.64
MMP12 P39900 2/20 0.64
MMP13 P45452 2/20 0.64
MAOB P27338 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685199 1.00 KDM4E (0.67) KDM4ELMNAFDPSCA12CA4
SCHEMBL5685437 0.95 FDPS (0.74) KDM4ELMNAFDPSCA12CA4
SCHEMBL5685435 0.95 FDPS (0.74) KDM4ELMNAFDPSCA12CA4
SCHEMBL5688117 0.94 KDM4E (0.76) KDM4ELMNAFDPSCA12CA4
SCHEMBL5688120 0.94 KDM4E (0.76) KDM4ELMNAFDPSCA12CA4
SCHEMBL5687914 0.92 LMNA (0.80) KDM4ELMNAFDPSCA12CA4
SCHEMBL5687918 0.92 LMNA (0.80) KDM4ELMNAFDPSCA12CA4
SCHEMBL1549322 0.88 LMNA (0.63) KDM4ELMNAFDPSCA12CA4
SCHEMBL1549319 0.88 LMNA (0.63) KDM4ELMNAFDPSCA12CA4
SCHEMBL16319134 0.88 LMNA (0.63) KDM4ELMNAFDPSCA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122065-A1 Amide compound and method of controlling plant disease with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed
EP-1577290-A1 AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2005-09-21 EP disclosed
WO-1997000249-A1 HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122065-A1 Amide compound and method of controlling plant disease with the same CBR3, C5, CLN6 KDM4E 3575/4885LMNA 2837/4885FDPS 1365/4885
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 KDM4E 2492/4885LMNA 1009/4885FDPS 2497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.