Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105384 | 0.80 | LOXL2 (0.60) | F2LOXL2AHR | |
| SCHEMBL3193871 | 0.80 | LOXL2 (0.60) | F2LOXL2AHR | |
| SCHEMBL28178529 | 0.80 | F2 (0.58) | F2SMN1; SMN2IMPDH2 | |
| SCHEMBL6824873 | 0.80 | LOXL2 (0.60) | F2SMN1; SMN2LOXL2 | |
| SCHEMBL6617237 | 0.80 | F2 (0.62) | F2SMN1; SMN2IMPDH2LOXL2 | |
| SCHEMBL6203738 | 0.80 | F2 (0.62) | F2SMN1; SMN2 | |
| Bromide SCHEMBL30437340 | 0.79 | LOXL2 (0.58) | F2LOXL2AHR | |
| Hydrochloric Acid SCHEMBL27754931 | 0.79 | LOXL2 (0.58) | F2LOXL2AHR | |
| SCHEMBL8932700 | 0.79 | F2 (0.61) | F2SMN1; SMN2IMPDH2MAOAMAOB | |
| SCHEMBL5792170 | 0.79 | F2 (0.61) | F2SMN1; SMN2IMPDH2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390354-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | Amgen Inc. (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002083653-A1 | TRIAZINYL ACRYLAMIDE DERIVATIVES AS KINASE INHIBITORS | AMGEN INC. (US) | 2002-10-24 | — | — | WO | disclosed |