Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105384 | 1.00 | LOXL2 (0.60) | LOXL2F2AHRIDO1OPRK1 | |
| Hydrochloric Acid SCHEMBL27754931 | 0.98 | LOXL2 (0.58) | LOXL2F2AHRIDO1OPRK1 | |
| Bromide SCHEMBL30437340 | 0.98 | LOXL2 (0.58) | LOXL2F2AHRIDO1OPRK1 | |
| Pyridine SCHEMBL27581580 | 0.88 | F2 (0.49) | LOXL2F2AHRIDO1OPRK1 | |
| SCHEMBL29403791 | 0.87 | LOXL2 (0.69) | LOXL2AHRPCSK9 | |
| SCHEMBL28338445 | 0.87 | LOXL2 (0.69) | LOXL2AHRPCSK9 | |
| SCHEMBL401081 | 0.87 | LOXL2 (0.69) | LOXL2AHRPCSK9 | |
| SCHEMBL6619148 | 0.85 | PCSK9 (0.57) | LOXL2F2AHRPCSK9 | |
| SCHEMBL6988526 | 0.85 | LOXL2 (0.53) | LOXL2F2AHRIDO1PCSK9 | |
| SCHEMBL7502282 | 0.85 | PCSK9 (0.57) | LOXL2F2AHRPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843548-A | Benzyl indole HDAC inhibitor and pharmaceutical application thereof | 南京医科大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117843548-A | Benzyl indole HDAC inhibitor and pharmaceutical application thereof | 南京医科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843548-A | Benzyl indole HDAC inhibitor and pharmaceutical application thereof | 南京医科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-116761598-A | Antiviral use of FABP4 modulating compounds | 新月生物科学 | 2023-09-15 | — | — | CN | disclosed |
| US-11339193-B2 | CDP protein secretion inhibitors | KEZAR LIFE SCIENCES (US) | 2022-05-24 | — | — | US | disclosed |
| CN-111087391-A | 4-indole quinazoline compound and preparation method and application thereof | 郑州大学 | 2020-05-01 | — | — | CN | disclosed |
| CN-102731450-A | Preparation method of benzofuran or indole | UNIV SUN YAT SEN | 2012-10-17 | — | — | CN | disclosed |
| CN-102438588-A | Methods of treating diseases using combination therapy | AMBIT BIOSCIENCES CORP | 2012-05-02 | — | — | CN | disclosed |
| EP-1443076-B1 | Chlorine containing stabilising system comprising nitrogen containing synergists for stabilisation of halogen containing polymers | CHEMTURA VINYL ADDITIVES GMBH (DE) | 2010-03-03 | — | — | EP | disclosed |
| US-7671118-B2 | Stabilizer system for stabilizing halogen-containing polymers | Chemtura Vinyl Additives, GmbH (DE) | 2010-03-02 | — | — | US | disclosed |
| WO-2002072684-A1 | CHLORATE-CONTAINING STABILIZER SYSTEM WITH NITROGEN-CONTAINING SYNERGISTS FOR STABILIZING HALOGEN-CONTAINING POLYMERS | CROMPTON VINYL ADDITIVES GMBH (DE) | 2002-09-19 | — | — | WO | disclosed |
| US-6441004-B1 | INDOLE DERIVATIVES AS ANTIINFLAMMATORY AGENTS | ZENECA LIMITED (GB) | 2002-08-27 | — | — | US | disclosed |
| US-20020019434-A1 | Indole derivatives having an antiviral activity | FUJISHITA TOSHIO (JP) | 2002-02-14 | — | — | US | disclosed |
| US-6333323-B1 | AS ANTI-HUMAN IMMUNODEFICIENCY VIRUS (HIV) DRUGS | SHIONOGI & CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| CN-1294580-A | Indole derivatives with antiviral activity | SHIONOGI & CO (JP) | 2001-05-09 | — | — | CN | disclosed |
| EP-1069111-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-1003504-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | AstraZeneca UK Limited (GB) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007351-A2 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ZENECA LIMITED (GB) | 1999-02-18 | — | — | WO | disclosed |
| CN-1163908-A | Photostable microcapsules | BASF AG (DE) | 1997-11-05 | — | — | CN | disclosed |
| CN-1143318-A | Transdermal device containing polyvinylpyrrolidone as dissolution enhancer | NOVEN PHARMA (US) | 1997-02-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339193-B2 | CDP protein secretion inhibitors | SEC61G, SEC61A1, SEC61B | LOXL2 3878/4885F2 4218/4885AHR 4065/4885 |
| US-20020019434-A1 | Indole derivatives having an antiviral activity | IDO1, IDO2, RCOR1 | LOXL2 215/4885F2 4037/4885AHR 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.