Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039384 | 0.87 | DHPS (0.62) | DHPS | |
| SCHEMBL4061451 | 0.85 | DHPS (0.58) | DHPS | |
| SCHEMBL6584269 | 0.83 | DHPS (0.62) | DHPS | |
| SCHEMBL4062097 | 0.81 | DHPS (0.51) | DHPS | |
| SCHEMBL7415372 | 0.78 | DHPS (0.50) | DHPS | |
| SCHEMBL6969386 | 0.76 | EDNRA (0.53) | DHPS | |
| SCHEMBL5036558 | 0.76 | DHPS (0.48) | DHPS | |
| SCHEMBL7698526 | 0.75 | DHPS (0.46) | DHPS | |
| SCHEMBL5633882 | 0.75 | DHPS (0.46) | DHPS | |
| SCHEMBL14278544 | 0.75 | DHPS (0.43) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897914-B1 | Process for the preparation of 2,5-disubstitued pyridines | HOFFMANN LA ROCHE (CH) | 2004-05-26 | — | — | EP | claimed |