Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 15/20 | 0.46 |
| ▸ | EDNRB | P24530 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | KLK3 | P07288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700308 | 0.88 | DHPS (0.51) | DHPSEDNRBEDNRA | |
| SCHEMBL7698527 | 0.84 | DHPS (0.65) | DHPS | |
| SCHEMBL4062097 | 0.84 | DHPS (0.51) | DHPSEDNRBEDNRA | |
| SCHEMBL4060942 | 0.84 | DHPS (0.56) | DHPSEDNRBEDNRA | |
| SCHEMBL4061451 | 0.82 | DHPS (0.58) | DHPSEDNRBEDNRA | |
| SCHEMBL5763617 | 0.79 | EDNRB (0.64) | DHPSEDNRBEDNRA | |
| SCHEMBL7694584 | 0.78 | EDNRB (0.44) | DHPSEDNRBEDNRAKLK3 | |
| SCHEMBL6585958 | 0.75 | DHPS (0.55) | DHPS | |
| SCHEMBL5036558 | 0.75 | DHPS (0.48) | DHPS | |
| SCHEMBL5097958 | 0.75 | KDM4E (0.42) | DHPSEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |