Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12425095 | 0.81 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1CYP1A2AKR1C3 | |
| SCHEMBL321574 | 0.80 | AR (0.50) | SLC1A3SLC1A2SLC1A1KDM4EAKR1C3 | |
| SCHEMBL2228777 | 0.79 | RORC (0.43) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| SCHEMBL2926653 | 0.78 | MAOA (0.54) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| SCHEMBL6498979 | 0.77 | IKBKB (0.48) | SLC1A3SLC1A2SLC1A1AKR1C3AKR1C2 | |
| SCHEMBL26375358 | 0.77 | PDE3B (0.44) | SLC1A3SLC1A2SLC1A1CYP1A2AKR1C3 | |
| SCHEMBL26375402 | 0.76 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| SCHEMBL179120 | 0.76 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1KDM4EALDH1A1 | |
| SCHEMBL6685777 | 0.75 | MAOB (0.56) | KDM4EALDH1A1CYP1A2MEN1CYP2D6 | |
| SCHEMBL16809158 | 0.75 | ESR2 (0.55) | SLC1A3SLC1A2SLC1A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |