Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.62 |
| ▸ | MMP2 | P08253 | 10/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
| ▸ | MMP14 | P50281 | 2/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6585173 | 0.90 | MMP3 (0.50) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6586655 | 0.90 | MMP3 (0.52) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6584490 | 0.78 | MMP3 (0.71) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6584000 | 0.78 | MMP3 (0.61) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL7404142 | 0.78 | MMP3 (0.70) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6585076 | 0.77 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6585851 | 0.76 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP14 | |
| Dimethylamine SCHEMBL6974207 | 0.76 | MMP3 (0.97) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6586804 | 0.75 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP14 | |
| SCHEMBL6973528 | 0.75 | MMP3 (1.00) | MMP3MMP2MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |