Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL6974207

CCOc1cccc(-c2ccc(C3CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC3)cc2C)c1.CNC

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MMP3 P08254 14/20 0.97
▸ MMP2 P08253 12/20 0.97
▸ MMP1 P03956 2/20 0.83
▸ MMP9 P14780 2/20 0.83
▸ MMP14 P50281 2/20 0.83
▸ DHODH Q02127 1/20 0.38
▸ CHRM3 P20309 1/20 0.37
▸ MMP13 P45452 1/20 0.36
▸ CTPS1 P17812 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6585076 0.98 MMP3 (1.00) MMP3MMP2MMP1MMP9MMP14
Dimethylamine SCHEMBL6437006 0.91 MMP2 (0.80) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6585851 0.91 MMP3 (1.00) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6972635 0.90 MMP3 (1.00) MMP3MMP2MMP1MMP9MMP14
Hydrochloric Acid SCHEMBL6962275 0.90 MMP3 (0.98) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6973528 0.89 MMP3 (1.00) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6586804 0.89 MMP3 (1.00) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6586134 0.89 MMP3 (0.83) MMP3MMP2MMP1MMP9MMP14
SCHEMBL6587846 0.89 MMP2 (0.83) MMP3MMP2MMP1MMP9MMP14
SCHEMBL7408826 0.89 MMP2 (0.82) MMP3MMP2MMP1MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181017-B1 METALLOPROTEASE INHIBITORS PFIZER LTD (GB) 2003-04-16 — — EP claimed