Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3832522 | 1.00 | MMP2 (0.41) | MMP2KMT2AKCNN4ANPEPCYP1A2 | |
| SCHEMBL3544176 | 0.91 | MMP2 (0.40) | MMP2KMT2AKCNN4ANPEPCYP1A2 | |
| SCHEMBL5202136 | 0.91 | MMP2 (0.40) | MMP2KMT2AKCNN4ANPEPCYP1A2 | |
| SCHEMBL3549930 | 0.86 | HTR3E (0.45) | MMP2KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30214730 | 0.86 | MMP2 (0.45) | MMP2KMT2AKCNN4ANPEPCYP3A4 | |
| SCHEMBL29276107 | 0.86 | MMP2 (0.45) | MMP2KMT2AKCNN4ANPEPCYP3A4 | |
| SCHEMBL29276109 | 0.86 | MMP2 (0.45) | MMP2KMT2AKCNN4ANPEPCYP3A4 | |
| SCHEMBL5205550 | 0.86 | HTR3E (0.45) | MMP2KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL992574 | 0.86 | KCNN4 (0.43) | MMP2KMT2AKCNN4ANPEPCYP1A2 | |
| SCHEMBL992573 | 0.86 | KCNN4 (0.43) | MMP2KMT2AKCNN4ANPEPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465864-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | Warner-Lambert Company LLC (US) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003045912-A1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER-LAMBERT COMPANY LLC (US) | 2003-06-05 | — | — | WO | disclosed |