Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619202 | 0.88 | POLB (0.62) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL6753939 | 0.87 | POLB (0.75) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL6589193 | 0.86 | POLB (0.69) | POLBDDAH1NPC1RAB9ANR2F2 | |
| SCHEMBL30701864 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL7856315 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL30701863 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL7856311 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL7854826 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL2331252 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 | |
| SCHEMBL27492580 | 0.84 | POLB (0.96) | POLBDDAH1NPC1RAB9ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815455-B1 | ANTIFOAM AGENTS OF MACROPHAGES; PREVENTING ARTERIOSCLEROSIS | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-09 | — | — | US | disclosed |
| EP-1197487-B1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | FUJI PHOTO FILM CO LTD (JP) | 2004-01-14 | — | — | EP | disclosed |
| EP-1197487-A1 | BENZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THE SAME | Fuji Photo Film Co., Ltd. (JP) | 2002-04-17 | — | — | EP | disclosed |