SCHEMBL1393290

SCHEMBL1393290

O=C(O)c1ccc(C(=O)C=Cc2ccc(F)cc2)cc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNFRSF1A P19438 2/20 0.86
CYP1B1 Q16678 2/20 0.69
CYP1A1 P04798 1/20 0.69
MAOB P27338 6/20 0.65
MAOA P21397 2/20 0.65
XDH P47989 1/20 0.64
CTSL P07711 1/20 0.61
CTSB P07858 1/20 0.61
F3 P13726 1/20 0.59
MAPT P10636 6/20 0.58
HSD11B1 P28845 1/20 0.58
CYP3A4 P08684 2/20 0.56
TP53 P04637 1/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.56
BLM P54132 1/20 0.56
CASP7 P55210 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25221701 1.00 TNFRSF1A (0.86) TNFRSF1ACYP1B1CYP1A1MAOBMAOA
SCHEMBL25221345 1.00 TNFRSF1A (0.86) TNFRSF1ACYP1B1CYP1A1MAOBMAOA
SCHEMBL1393287 1.00 TNFRSF1A (0.86) TNFRSF1ACYP1B1CYP1A1MAOBMAOA
SCHEMBL7196521 0.93 TNFRSF1A (1.00) TNFRSF1ACYP1B1CYP1A1MAOBMAOA
SCHEMBL5593308 0.93 TNFRSF1A (1.00) TNFRSF1ACYP1B1CYP1A1MAOBMAOA
SCHEMBL25201250 0.91 XDH (0.74) TNFRSF1ACYP1B1MAOBMAOAXDH
SCHEMBL25195971 0.91 XDH (0.74) TNFRSF1ACYP1B1MAOBMAOAXDH
SCHEMBL2997293 0.91 XDH (0.74) TNFRSF1ACYP1B1MAOBMAOAXDH
SCHEMBL2997295 0.91 XDH (0.74) TNFRSF1ACYP1B1MAOBMAOAXDH
SCHEMBL10528715 0.91 XDH (0.74) TNFRSF1ACYP1B1MAOBMAOAXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
EP-2592065-B1 COMPOUND HAVING A PHOTOREACTIVE FUNCTIONAL GROUP, A PHOTOREACTIVE POLYMER, AND AN ALIGNMENT LAYER INCLUDING SAME LG CHEMICAL LTD (KR) 2018-11-14 EP disclosed
US-8449954-B2 Compound having photoreactive functional group, photoreactive polymer, and alignment film comprising the same LG CHEM, LTD. (KR) 2013-05-28 US disclosed
EP-2592065-A2 COMPOUND HAVING A PHOTOREACTIVE FUNCTIONAL GROUP, A PHOTOREACTIVE POLYMER, AND AN ALIGNMENT LAYER INCLUDING SAME LG Chem, Ltd. (KR) 2013-05-15 EP disclosed
US-20120010381-A1 COMPOUND HAVING PHOTOREACTIVE FUNCTIONAL GROUP, PHOTOREACTIVE POLYMER, AND ALIGNMENT FILM COMPRISING THE SAME LG CHEM, LTD. (KR) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 TNFRSF1A 3485/4885CYP1B1 1027/4885CYP1A1 1747/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 TNFRSF1A 3485/4885CYP1B1 1027/4885CYP1A1 1747/4885
US-20120010381-A1 COMPOUND HAVING PHOTOREACTIVE FUNCTIONAL GROUP, PHOTOREACTIVE POLYMER, AND ALIGNMENT FILM COMPRISING THE SAME PIN1, CCDC47, VCL TNFRSF1A 3545/4885CYP1B1 2924/4885CYP1A1 3796/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.