Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | BCHE | P06276 | 3/20 | 0.75 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.75 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.71 |
| ▸ | RELA | Q04206 | 2/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Fluoro Chalcone SCHEMBL10363601 | 1.00 | TNFRSF1A (0.82) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| 4-Fluoro Chalcone SCHEMBL657888 | 1.00 | TNFRSF1A (0.82) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL6586583 | 0.93 | TNFRSF1A (0.82) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL11797296 | 0.93 | TNFRSF1A (0.82) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL6593521 | 0.93 | TNFRSF1A (0.82) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL5593308 | 0.90 | TNFRSF1A (1.00) | TNFRSF1AMAOBMAPTCYP1B1CYP3A4 | |
| SCHEMBL7196521 | 0.90 | TNFRSF1A (1.00) | TNFRSF1AMAOBMAPTCYP1B1CYP3A4 | |
| SCHEMBL8431772 | 0.90 | CYP1B1 (0.91) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL9915665 | 0.90 | CYP1B1 (0.91) | TNFRSF1AMAOBMAPTCYP1B1LMNA | |
| SCHEMBL25221701 | 0.87 | TNFRSF1A (0.86) | TNFRSF1AMAOBMAPTCYP1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | claimed |
| CN-111233645-A | Method for preparing tri-substituted cyclopentene by MBH/Wittig domino reaction of vinylon insertion | 浙江大学 | 2020-06-05 | — | — | CN | claimed |
| EP-0926951-B1 | TREATING PULMONARY DISEASES MEDIATED BY POLYUNSATURATED LIPID METABOLITES AND ASSAYS FOR EPOXIDE HYDROLASE INHIBITORS | UNIV CALIFORNIA (US) | 2004-04-21 | — | — | EP | claimed |
| EP-4567018-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-06-11 | — | — | EP | disclosed |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | DAIKIN INDUSTRIES, LTD. (JP) | 2025-02-13 | — | — | US | disclosed |
| US-12162854-B2 | Production method for fluoromethyl derivative | DAIKIN INDUSTRIES, LTD. (JP) | 2024-12-10 | — | — | US | disclosed |
| WO-2024029525-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | ダイキン工業株式会社 | 2024-02-08 | — | — | WO | disclosed |
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | disclosed |
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| US-11661407-B2 | Process for the preparation of pyrylium salts | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-05-30 | — | — | US | disclosed |
| CN-114805044-A | Novel method for synthesizing dibromo compound | 兰州大学 | 2022-07-29 | — | — | CN | disclosed |
| US-5182303-A | Substituted semicarbazone arthropodicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |
| EP-0444533-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| WO-1991007382-A1 | SUBSTITUTED SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-30 | — | — | WO | disclosed |
| US-4973704-A | ANTICHOLESTEROL AGENTS | SANDOZ PHARM. CORP. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0377304-A2 | Substituted semicarbazone arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-11 | — | — | EP | disclosed |
| EP-0356788-A2 | Quinoline and pyridine anchors for HMG-CoA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4851427-A | INHJIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANDOZ PHARM. CORP. (US) | 1989-07-25 | — | — | US | disclosed |
| EP-0221025-A1 | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals | SANDOZ AG (CH) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12162854-B2 | Production method for fluoromethyl derivative | AFF1, AFF2, ROS1 | TNFRSF1A 4784/4885MAOB 20/4885MAPT 3085/4885 |
| US-20250051299-A1 | PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE | AFF1, AFF2, ROS1 | TNFRSF1A 4784/4885MAOB 20/4885MAPT 3085/4885 |
| US-11661407-B2 | Process for the preparation of pyrylium salts | SF3B5, IPO5, CYP4F11 | TNFRSF1A 3244/4885MAOB 2613/4885MAPT 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.