Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.52 |
| ▸ | MMP3 | P08254 | 8/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | USP5 | P45974 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586243 | 0.93 | MMP2 (0.49) | MMP2MMP3MMP1MMP9MMP14 | |
| Hydrochloric Acid SCHEMBL6582464 | 0.93 | MMP2 (0.49) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6587738 | 0.92 | MMP2 (0.53) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6584479 | 0.90 | MMP2 (0.56) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6584427 | 0.90 | MMP2 (0.50) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6586370 | 0.89 | MMP2 (0.56) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434211 | 0.87 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6437315 | 0.87 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6434216 | 0.87 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6590241 | 0.86 | MMP2 (0.51) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |