Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586645 | 1.00 | BRD4 (0.46) | BRD4TDP1L3MBTL1USP2LMNA | |
| SCHEMBL6584406 | 0.91 | LMNA (0.48) | BRD4TDP1L3MBTL1USP2LMNA | |
| SCHEMBL6584410 | 0.91 | LMNA (0.48) | BRD4TDP1L3MBTL1USP2LMNA | |
| SCHEMBL6589729 | 0.85 | BRD4 (0.63) | BRD4TDP1L3MBTL1CYP19A1 | |
| SCHEMBL6589731 | 0.85 | BRD4 (0.63) | BRD4TDP1L3MBTL1CYP19A1 | |
| SCHEMBL6080348 | 0.81 | LMNA (0.52) | BRD4TDP1L3MBTL1USP2LMNA | |
| SCHEMBL6587301 | 0.80 | LPAR1 (0.49) | TDP1L3MBTL1LMNA | |
| SCHEMBL6587300 | 0.80 | LPAR1 (0.49) | TDP1L3MBTL1LMNA | |
| SCHEMBL6588706 | 0.79 | BRD4 (0.46) | BRD4TDP1L3MBTL1LMNA | |
| SCHEMBL6588711 | 0.79 | BRD4 (0.46) | BRD4TDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |