Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587301 | 1.00 | LPAR1 (0.49) | LPAR1GAAALDH1A1MAPTNPC1 | |
| SCHEMBL6587807 | 0.89 | KMT2A (0.48) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6587809 | 0.89 | KMT2A (0.48) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6587522 | 0.84 | EPHX1 (0.53) | LPAR1GAAALDH1A1MAPTNPC1 | |
| SCHEMBL6585742 | 0.84 | EPHX1 (0.53) | LPAR1GAAALDH1A1MAPTNPC1 | |
| SCHEMBL6585901 | 0.82 | ALDH1A1 (0.48) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL6585904 | 0.82 | ALDH1A1 (0.48) | GAAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2076016 | 0.81 | LPAR1 (0.57) | LPAR1GAAALDH1A1MAPTNPC1 | |
| SCHEMBL31079121 | 0.81 | LPAR1 (0.57) | LPAR1GAAALDH1A1MAPTNPC1 | |
| SCHEMBL6586645 | 0.80 | BRD4 (0.46) | LMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |