Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586699 | 0.89 | SORD (0.52) | SORDGPR119ALDH1A1 | |
| SCHEMBL6586693 | 0.89 | SORD (0.52) | SORDGPR119ALDH1A1 | |
| SCHEMBL6584718 | 0.87 | SORD (0.69) | SORDGPR119 | |
| SCHEMBL6586365 | 0.82 | HRH4 (0.46) | SORD | |
| SCHEMBL6587251 | 0.82 | HRH4 (0.46) | SORD | |
| SCHEMBL6589084 | 0.82 | HRH4 (0.46) | SORD | |
| SCHEMBL6293425 | 0.78 | SORD (0.40) | SORDALDH1A1MAPT | |
| SCHEMBL6293162 | 0.76 | SORD (0.67) | SORD | |
| SCHEMBL6293163 | 0.76 | SORD (0.67) | SORD | |
| SCHEMBL6338336 | 0.75 | AVPR1A (0.42) | SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041068-B1 | Compounds for treating and preventing diabetic complications | PFIZER PROD INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-6294538-B1 | ANTIDIABETIC AGENTS AND DIABETIC NEUROPATHY, TREATMENT WITH OXIDOREDUCTASE ENZYMES | PFIZER INC. | 2001-09-25 | — | — | US | disclosed |
| EP-1041068-A1 | Compounds for treating and preventing diabetic complications | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |