Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | SORD | Q00796 | 12/20 | 0.43 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586365 | 1.00 | HRH4 (0.46) | HRH4HRH3SORDPRKD1PRKD2 | |
| SCHEMBL6587251 | 1.00 | HRH4 (0.46) | HRH4HRH3SORDPRKD1PRKD2 | |
| SCHEMBL6294656 | 0.85 | HRH4 (0.48) | HRH4HRH3SORDPRKD1PRKD2 | |
| SCHEMBL6294658 | 0.85 | HRH4 (0.48) | HRH4HRH3SORDPRKD1PRKD2 | |
| SCHEMBL7493841 | 0.84 | SORD (0.33) | HRH4SORD | |
| SCHEMBL6293204 | 0.84 | SORD (0.33) | HRH4SORD | |
| SCHEMBL6586699 | 0.83 | SORD (0.52) | SORD | |
| SCHEMBL6586693 | 0.83 | SORD (0.52) | SORD | |
| SCHEMBL6586908 | 0.82 | SORD (0.51) | SORD | |
| SCHEMBL6293551 | 0.82 | PRKCQ (0.46) | HRH4SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041068-B1 | Compounds for treating and preventing diabetic complications | PFIZER PROD INC (US) | 2004-04-14 | — | — | EP | disclosed |
| US-6294538-B1 | ANTIDIABETIC AGENTS AND DIABETIC NEUROPATHY, TREATMENT WITH OXIDOREDUCTASE ENZYMES | PFIZER INC. | 2001-09-25 | — | — | US | disclosed |
| EP-1041068-A1 | Compounds for treating and preventing diabetic complications | Pfizer Products Inc. (US) | 2000-10-04 | — | — | EP | disclosed |