Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.75 |
| ▸ | CTSK | P43235 | 15/20 | 0.75 |
| ▸ | CTSL | P07711 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872650 | 1.00 | CTSS (0.75) | CTSSCTSKCTSLCTSB | |
| SCHEMBL20143076 | 0.84 | MEN1 (0.55) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6587122 | 0.82 | CTSS (0.51) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5530693 | 0.82 | CTSS (0.69) | CTSSCTSKCTSLCTSB | |
| SCHEMBL12179560 | 0.81 | TDP1 (0.58) | CTSSCTSK | |
| SCHEMBL1565973 | 0.81 | CTSS (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL13314166 | 0.81 | CTSS (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL16504634 | 0.81 | MEN1 (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL16504731 | 0.81 | MEN1 (0.58) | CTSSCTSKCTSLCTSB | |
| SCHEMBL14378789 | 0.81 | MEN1 (0.58) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178958-B1 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2004-02-18 | — | — | EP | disclosed |